Fibrinogen from Bovine, fraction I
Fibrinogen
CAS: 9001-32-5
Molecular Formula: C6H14O6
Fibrinogen from Bovine, fraction I - Names and Identifiers
Fibrinogen from Bovine, fraction I - Physico-chemical Properties
| Molecular Formula | C6H14O6 |
| Molar Mass | 182.17176 |
| Solubility | 0.9% NaCl: soluble |
| Appearance | powder |
| Color | white |
| Storage Condition | -20°C |
| MDL | MFCD00131060 |
| Physical and Chemical Properties | This product is a white powder or loose and fragile block, slightly soluble in water, and is a colorless, odorless, clear and slightly opalescent viscous liquid after dissolution, and there may be a trace of small insoluble protein. This product is obtained from human plasma treatment. The purity of fibrinogen is above 60%. Also known as coagulation factor: it plays an important role in maintaining coagulation and hemostasis. When the blood concentration is lower than 680mg · L-1, the blood cannot maintain normal coagulation. Intravenous injection of this product can increase the concentration of fibrinogen in blood. Under the action of thrombin eggs, the protein in the sol state is transformed into gel-like (insoluble fibrin), which promotes blood coagulation. To achieve the purpose of coagulation. It has special effects on coagulation disorders caused by lack of fibrinogen. |
Fibrinogen from Bovine, fraction I - Risk and Safety
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
| TSCA | Yes |
Fibrinogen from Bovine, fraction I - Reference
| Reference Show more | 1. Li Min, Li Xiao, Zhou Jing et al. Optimization and comparison of extraction process of leech from longshengzhi capsules by R language and orthogonal test [J]. Chinese herbal medicine 2018 v.41;No.407(01):165-168. 2. Su Min Yu Hong Liang Wang Shang et al. Preliminary Study on low-cost production of Nattokinase [J]. Food industry 2017(10):48-52. 3. Wang Zhengjun, Li Bo, Guo Liwei, etc. Study on the factors affecting the fibrinolytic activity of pepsin and trypsin and the inactivation of fibrinolytic activity [J]. Chinese Herbal Medicine, 2016, 47(01):56-66. 4. Zhang Kewei, Zhong Yuyan, Cao Honghong, et al. Quality Analysis of Leech before and after processing [J]. Chinese traditional medicines, 2018, 40(10):134-139. 5. He Mengxue, Li Zeyou. Extraction and SDS-PAGE electrophoretic determination of antithrombin components from Hainan phifusa nigholata [J]. Chinese Journal of Tropical Biology, 2019, 010(002):204-207. 6. Tian Zhou, Li Bo, Guo Liwei, et al. Effect and mechanism of wet superfine grinding and water decoction extraction method on thrombolysis and anticoagulation activity of rat protein [J]. New Traditional Chinese Medicine and Clinical Pharmacology, 2015(02):169-174. 7. Zhang, Xing-can. A preliminary study on the stability of Nattokinase in fermented bean curd [J]. China condiment, 2015,40(02):72-76 80. 8. Zhao Moming, Zou Ying, Lin Xinzhu, Wu Jian. Nattokinase production and metabolic characteristics analysis of buckwheat fermented by Bacillus natto [J]. Food Science, 2019,40(04):178-185. 9. Qian Zedong, Zhang Youhong, Lu Yubing, Zhu Na, Tian Li. Isolation, screening and identification of Bacillus natto [J]. Chemistry and bioengineering, 2018,35(08):41-44. 10. Zhang Dendan, du Wenfang, Zhao Jun, et al. Expression of reteplase in Pichia pastoris [J]. Microbiology, 2017(9). 11. Han Cuiping, Liu Qingguan, Liu Chang, etc. Selection of cryoprotectants for black bean Nattokinase [J]. Chinese Journal of Food Science, 2019, 26 (8). 12. Bai Jingzhi, Liu Yongjie. Expression and significance of IL-6 RF ACCP and coagulation indexes in patients with coronary heart disease complicated with rheumatoid arthritis [J]. Chinese Journal of Health Engineering 2020 v.19(03):142-144. 13. Yin Mengwen, Zhou Qian, Lei Yan, et al. Screening and safety evaluation of fibrinolytic enzyme-producing lactic acid bacteria [J]. Food and machinery 2017 033(010):28-33. 14. Tian Li, Lu Min, male, Zhu Jian, et al. Optimization of fermentation conditions of Bacillus subtilis gene engineering strain producing Nattokinase by response surface methodology [J]. Journal of Wuhan Institute of Technology 2018 v.40;No.209(06):33-40. 15. Lin, Chen, Shui, Chen, Wei. Construction of recombinant bacteria secreting hirudin Ⅱ [J]. Journal of Zhejiang University of Technology 2014 42(1):50-53. 16. Long Jiyan, Dai Ming, Zhong Yao, Li Mengxin, Jiang Yongmei. Screening of natto fermentation materials and development of functional products [J]. Biochemical Engineering, 2020,6(06):47-50. 17. Zhang Liqiang, ran Maofang, Wang Songtao, Liu Guangqian, Ma Zhuo, Ren Jianbo, Shen Caihong, Xu Tao. Isolation and identification of fibrinolytic enzyme-producing strain from Luzhou Laojiao Daqu [J]. Brewing Science & Technology, 2021(03):17-24. 18. Li xiulang, Li Qianwen, Zhu Yu, Han Xiaoyun, Sun Qingshen, Song Yong. Extraction and characterization of Nattokinase from vegetable soybean fermented by Bacillus natto [J]. China Brewing, 2020,39(12):106-112. 19. Tian, Li, Wenke Zhou, and Youhong Zhang. "Construction of a genetically engineered strain of nattokinase and assessment of its fibrinolytic activity." African Journal of Microbiology Research 13.27 (2019): 488-499.https://doi.org/10.5897/AJMR2019.9181 20. Wu, Xiaotian, et al. "Antifouling zwitterionic dextran micelles for efficient loading DOX." Carbohydrate polymers 191 (2018): 136-141.https://doi.org/10.1016/j.carbpol.2018.03.020 21. Ji, Mingbo et al. "Improved blood compatibility of polysulfone membrane by anticoagulant protein immobilization." Colloids and Surfaces B: Biointerfaces 175 (2019): 586-595.https://doi.org/10.1016/j.colsurfb.2018.12.026 22. Chen, Xiaofeng, et al. "Differences in zwitterionic sulfobetaine and carboxybetaine dextran-based hydrogels." Langmuir 35.5 (2018): 1475-1482. 23. [IF=9.381] Xiaotian Wu et al."Antifouling zwitterionic dextran micelles for efficient loading DOX."Carbohyd Polym. 2018 Jul;191:136 24. [IF=8.897] Liu Liu et al."Design of dual metal ions/dual amino acids integrated photoluminescent logic gate by high-molecular weight protein-localized Au nanoclusters."Nano Res. 2018 Jan;11(1):311-322 25. [IF=6.331] Chang-Jiang Pan et al."Blood compatibility and interaction with endothelial cells of titanium modified by sequential immobilization of poly (ethylene glycol) and heparin."J Mater Chem B. 2014 Jan;2(7):892-902 26. [IF=3.882] Xiaofeng Chen et al."Differences in Zwitterionic Sulfobetaine and Carboxybetaine Dextran-Based Hydrogels."Langmuir. 2019;35(5):1475-1482 27. [IF=3.361] Zifeng Zhang et al."Antifouling hydrogel film based on a sandwich array for salivary glucose monitoring."Rsc Adv. 2021 Aug;11(44):27561-27569 28. [IF=3.361] Shiwen Wang et al."Low-fouling CNT-PEG-hydrogel coated quartz crystal microbalance sensor for saliva glucose detection."Rsc Adv. 2021 Jun;11(37):22556-22564 29. [IF=9.229] Miaomiao Han et al."Amyloid Protein-Biofunctionalized Polydopamine Nanoparticles Demonstrate Minimal Plasma Protein Fouling and Efficient Photothermal Therapy."Acs Appl Mater Inter. 2022;XXXX(XXX):XXX-XXX |
Fibrinogen from Bovine, fraction I - Nature
Open Data Verified Data
- This product is a white powder or loose and fragile mass, slightly soluble in water, colorless, odorless, clear and slightly opalescent viscous liquid after dissolution, with trace amounts of small insoluble proteins.
- This product was obtained from the treatment of human plasma. The purity of fibrinogen was more than 60%. Also known as coagulation factor gene. It plays an important role in maintaining normal blood coagulation and hemostasis. When the blood concentration is less than L-1 mg., the blood can not be normal coagulation. Intravenous injection of this product can increase the blood fibrinogen concentration. Under the action of thrombin, fibrinogen in a sol state is converted into a gel form (insoluble fibrin), which promotes blood coagulation. To achieve the purpose of hemostasis. The lack of fibrinogen caused by coagulation disorders have special effects.
Last Update：2024-01-02 23:10:35
Fibrinogen from Bovine, fraction I - Use
Open Data Verified Data
- is mainly used to rescue coagulation disorders caused by fibrinogen deficiency caused by pregnancy poisoning, placental disc early stripping, stillbirth, postpartum hemorrhage and major surgery, trauma, internal injury bleeding. Also used to prevent the first, acquired chronic low fibrinogen blood caused by abnormal bleeding.
- usage and dose of intravenous drip, 1~6G each time, 3~8g daily. The attached water for injection is heated to 25~30 ℃ to dissolve the product, and the blood transfusion device with filter is used immediately for intravenous drip, and the speed should not exceed 40~60 drops per minute. This product absorbs thrombin from the dry preparation Fi-brin,Foam human, insoluble in water, can be used locally for bleeding, especially for brain, liver, kidney and other surgery to take other hemostatic methods ineffective, it will be absorbed naturally at a certain time.
- preparation of human fibrinogen powder for injection, specifications are lg/bottle, 1.5g/bottle, 2.5g/bottle; Freeze-dried human fibrinogen, specifications are lg/bottle, 1.5g/bottle.
Last Update：2022-01-01 11:13:45
Fibrinogen from Bovine, fraction I - Safety
Open Data Verified Data
- may have cyanosis, tachycardia, hepatitis B. Intravascular coagulation may occur with rapid excessive infusion. To have thrombophlebitis, thrombosis and myocardial infarction or cardiac insufficiency in patients with non-use.
- sealed at 2-10 ℃, stored in dark, denatured above 56 ℃.
Last Update：2022-01-01 11:13:46
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Featured ProductsMultiple SpecificationsSpot supply
Product Name: Fibrinogen from human plasma Visit Supplier Webpage Request for quotationCAS: 9001-32-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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